Coronaviruses have four structural proteins (E,M,N,S protein) that can bind to membrane receptors on host cells, thereby mediating the fusion of the virus and the cell membrane. After the S protein of SARS-CoV-2 interacts with ACE2 and then enters the cell through endocytosis, Cathepsin B/L degrades the Spike protein to release nucleic acids of virus. In addition, CD147 also plays a functional role in promoting SARS-CoV-2 invasion into host cells.
|Cat. No.||SARS-CoV-2 Host Associated Proteins||Pack Size|
|KPT032068||Recombinant Human ACE2 Protein (His Tag)||50 ug|
|KPT032179||Recombinant Human Cathepsin B/CTSB Protein (His Tag)||50 ug|
|KPT040956||Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)||50 ug|
|KPT032182||Recombinant Human Cathepsin L/CTSL Protein (His Tag)||50 ug|
|KPT041247||Recombinant Mouse Cathepsin L/CTSL Protein (aa 18-334, His Tag)||50 ug|
|KPT032377||Recombinant Human CD147/Basigin Protein (His Tag)||50 ug|
|KPT041223||Recombinant Mouse CD147/Basigin Protein (His Tag)||50 ug|
Total 7 products.
Dr Jayaraman D. Lead Scientist, leading CRO companyI have been working with a team from KRISHGEN on an assay development and customization before giving us. The project was complicated and needed technical expertise in immunology. I was very pleased with their technical competence and also mastering immunology and delivering a tough project to us on time. Their rigor, punctuality and expertise have been a recipe for the high standards, I would expect for such project from them. Kudos, Krishgen Team!!!
Mr Ramesh Sravanan, VP-Supply ChainThe expertise and command on the logistics chain including the regulatory guidelines from Krishgen is something we admire. As they often indicate, let us do the supplies, and let your team focus on science … is really something the company works on. Delivering consistently, with less than 1% error or delay consistently is the key to their success.
Dr Keith Stevens, visiting Scientist, Norfolk University, UKTo have a company understand science and work with them, is a pleasure. Krishgen not only sells but understands what it sells in terms of the complex cutting edge sceince.
Mellisa Karlowski, Lead Researcher, east coast US CROThe company is good on understanding its customers, is transparent and speaks science. This makes it easier for us to work with them.
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