Human plasma kallikrein, a serine protease, is first synthesized as an inactive plasma prekallikrein in liver and circulates in the plasma. Once activated by activated coagulation factor XII (FXIIa), plasma kallikrein releases bradykinin (an inflammatory mediator) from high molecular weight kininogen (HMWK).
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KRISHZYME™ Prekallikrein Activator Assay Kit
SKU: KBBA30EP
Rs 129,600.00
KRISHZYME Plasma Kallikrein Activitor Assay Kit utilizes the ability of active plasma kallikrein to cleave a synthetic pNA-based peptide substrate to release pNA, which can be easily quantified using a microplate reader. The kit is easy-to-use and can detect PK activity of purified plasma kallikrein and plasma samples according to the procedure recommended by the European Pharmacopoeia.
About the kit:
– Uses high quality reagents from our vendor partner in the US, which ensures higher specificity, and low cross reactivity.
– Recovery rates are between 85 – 115%
– Ready to use with a standard protocol with break-apart pre-coated wells
– Validated as per US FDA guidelines for Bioassays
– Optimized for matrix effects to ensure higher sensitivity.
– Shelf life: 1 year
Availability: 3 – 4 Weeks | Pack Size: 1 x 96 wells
Additional information
| Sample Type | Cell Culture Supernatant and Pharmaceutical Preparations |
|---|---|
| Detection Method | Colorimetric |
| Regulatory Status | For Research Use Only |
| Storage Temperature | Store the unopened product at 2-8 Deg C. Do not use past expiration date. |
