Complement System
The complement system in blood plasma is a major mediator of innate immune defence. The function of complement is to recognize, then opsonize or lyse, particulate materials, including bacteria, yeasts and other micro-organisms, host cell debris and altered host cells. Complement is a system of plasma proteins that can be activated directly by pathogens or indirectly by pathogen-bound antibodies, leading to a cascade of reactions that occurs on the surface of pathogens and generates active components with various effector functions. There are three pathways of complement activation: the classical pathway, which is triggered directly by pathogen or indirectly by antibody binding to the pathogen surface; the MB-lectin pathway; and the alternative pathway, which also provides an amplification loop for the other two pathways. All three pathways can be initiated independently of antibodies as part of innate immunity.
Krishgen offers a range of ELISA for all three pathways of the complement system. In case you are unable to find the ELISA you require, please get in touch with us at info@krishgen.com.
| Marker Analyte | Human | Rat | Mouse | Porcine | Goat | Bovine | Others |
|---|---|---|---|---|---|---|---|
| ACT | |||||||
| C1 inhibitor | |||||||
| C1QA | KBH5085 | KLM1964 | KLP0550 | KBH12277 | |||
| C1QB | KLR1925 | ||||||
| C1QC | KBH5086 | ||||||
| C1QL1 | KBH6573 | ||||||
| KBH9629 | |||||||
| C1R | |||||||
| C1S | KBH5096 | ||||||
| C1SA | |||||||
| C2 | KBH3040 | ||||||
| C3AR1 | KBH6574 | ||||||
| C5 | KBH0347 | ||||||
| C5AR1 | KBH6576 | ||||||
| C6 | KBH5098 | ||||||
| C7 | KBH0340 | ||||||
| C8A | KBH5099 | ||||||
| C8B | KBH5112 | ||||||
| C8G | KBH5113 | ||||||
| C9 | KBH5097 | KLM1968 | |||||
| Calreticulin | KBH4002 | KLR0242 | KLM1897 | ||||
| CD11b | KBH0308 | KLR0751 | KLM2155 | KLB0308 | |||
| CD11c | |||||||
| CD18 | KBH4529 | KLR2082 | KLP0077 | KLG0098 | KBH13712 (Ca) | ||
| KBH0237 | |||||||
| CD35 | |||||||
| CD46 | |||||||
| CD55 | |||||||
| CD59 | KBH4730 | ||||||
| CD59a | |||||||
| CD93 | KBH4584 | ||||||
| CFB | KBH0379 | KBH13273 | KBH11778 | KBH12366 | KBH12585 (Ra) | ||
| KBH13698 (Ca) | |||||||
| KBH13864 (Ch) | |||||||
| CFD | KBH0319 | KLR1114 | KLM1969 | KLP0412 | KLB2011 | ||
| KLM1402 | |||||||
| CFH | KBH0324 | KLR0163 | KLM0592 | ||||
| CFHR1 | |||||||
| CFP | KBH4268 | KLM2370 | |||||
| Clusterin | KBH1189 | KBH12801 | KLM1943 | KLP0545 | KBH12801 (Ca) | ||
| KLS0161 (Sh) | |||||||
| CPN1 | KBH2435 | KBH12935 | |||||
| KBH6603 | |||||||
| CR1L | |||||||
| CR2 | KBH9632 | KLM1971 | |||||
| FHL1 | KBH5303 | ||||||
| MASP2 | KBH5633 | ||||||
| MBL1 | KLB2057 | ||||||
| MBL2 | KBH4304 | ||||||
| PROS1 | |||||||
| Vitronectin | KBH0284 | KLM1409 | KLN0117 (Ca) | ||||
| VSIG4 | KLM2589 |