KRIBIOLISA Protein L Ligand ELISA kit

The new KRIBIOLISA Protein L Ligand Leakage kit has now been completely validated and is available in stock. It now comes with an increased calibrator range, more sensitivity and new, competitive pricing.

Protein L was first isolated from the surface of bacterial species Pepto-streptococcus magnus and is used as ligand in chromatography media for capture of Ig and Ig fragments. It consists of 719 amino acid residues. Protein L binds to the variable region of the kappa light chain of the antibody, without interfering with the antigen binding site. This allows Protein L to bind a wider range of Ig classes and subclasses than other antibody-binding proteins. In addition, Protein L also binds antibody fragments such as Fabs, single-chain variable fragments and domain antibodies which contain the kappa light chain.

The KRIBIOLISA™ Protein L Ligand Detection ELISA Kit is a quantitative enzyme-linked immunosorbent assay. This ELISA-kit has been designed to detect and quantify ligand leakage in eluates from Protein L affinity chromatography medium containing immunoglobulin (Ig) or Ig fragments.