Description
Beta-trace protein (BTP), also known as prostaglandin D synthase, is a low molecular weight protein predominantly produced by the choroid plexus of the brain and the proximal tubules of the kidneys. In renal physiology, BTP serves as a biomarker for glomerular filtration rate (GFR) and tubular function. The Human BTP ELISA Kit provides a reliable method for measuring BTP concentrations in human serum and urine samples, facilitating studies aimed at understanding kidney function, disease progression, and therapeutic interventions.
Pathways and Relevance:
The Human BTP ELISA Kit is instrumental in elucidating pathways associated with renal filtration, tubular reabsorption, and kidney injury in various renal disorders such as chronic kidney disease (CKD), acute kidney injury (AKI), and diabetic nephropathy. By quantifying BTP levels, researchers can assess renal function, monitor disease progression, and evaluate treatment responses. Furthermore, BTP serves as a prognostic marker for renal outcomes and mortality, highlighting its relevance in clinical practice and translational research. Ongoing research endeavors include investigating the mechanisms underlying BTP regulation, identifying biomarkers for early detection of renal dysfunction, and developing targeted therapies to preserve kidney function and mitigate disease progression. Additionally, researchers are exploring the potential of BTP as a non-invasive biomarker for assessing kidney function and predicting clinical outcomes in patients with renal disorders, driving innovation and shaping the future of nephrology and renal transplantation.
Validated against seven points for a “GOLD RING” Standard Quality ELISA – the benchmark sign for Krishgen Quality. The The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be human serum, plasma, biological fluids and cell culture supernatant. The kit uses indirect sandwich assay with double antibodies – capture and detection to ensure a high degree of sensitivity and specificity in the estimation of Beta-Trace Protein (BTP);
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