Description
Background:
Monalizumab is a monoclonal antibody designed to target the NKG2A receptor, an inhibitory receptor expressed on natural killer (NK) cells and certain T cells. By blocking NKG2A, monalizumab aims to enhance the anti-tumor immune response. The antibody has shown promise in cancer immunotherapy, particularly in combination with other immune checkpoint inhibitors. The application of monalizumab lies in its potential to boost the activity of immune cells against cancer cells. Clinical trials are underway to evaluate its efficacy in various solid tumors and hematological malignancies. This immunotherapeutic approach seeks to overcome the immunosuppressive mechanisms employed by tumors, contributing to a more effective immune response against cancer.