KRIBIOLISA™ Samrotamab Vedotin ELISA

SKU: KBI1612 Category:

Enzyme Immunoassay for the estimation of Samrotamab in serum and plasma.

About the kit:
– Uses anti-idiotypic monoclonal antibodies which ensures higher specificity, and low cross reactivity.
– Recovery rates are between 85 – 115%
– Validated as per US FDA guidelines for Bioassays
– Precision CV<10%

Availability: 3 – 4 weeks | Pack Size: 1 x 96 wells


Description

Background:
Samrotamab vedotin, also known as ABBV-085 is an antibody-drug conjugate or ADC being developed by AbbVie. the monoclonal antibody moiety of ABBV-085 targets and binds to leucine-rich repeat containing 15 (LRRC15) expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the LRRC15-expressing cancer cells, through an as of yet unknown mechanism of action (MOA).

Intended Use:
For Estimation of Samrotamab in human serum and plasma. Krishgen’s range of KRIBIOLISA kits are developed using the high quality raw materials and are thoroughly validated for accuracy and precison. They allow quantification of serum or plasma protein drug levels, and can be used for biosimilar and generics research to understand pharmacokinetic properties of the drug. Please note the kit has not been optimized to be used for any other animal species. Should you require a specific sera tested, please connect with us for optimisation.

If you have published a paper by using any of our ELISA since 01/01/2023, kindly fill out the “Krishgen Publication Reward Application Form” with complete information and send it by at email: info@krishgen.com, with the subject “Krishgen Publication Reward”. We will get back to you with the Amazon / Krishgen Credit Reward after we confirm it ASAP!

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Additional information

Sample Type

Serum (100 ul), EDTA Plasma (100 ul), Heparin Plasma (100 ul), Citrate Plasma (100 ul)

Calibration Range

0 ng/ml – 2000 ng/ml

Specificity

80% – 120% to Samrotamab

Cross Reactivity

< 0.5% cross-reactivity observed with related biomarker.

Interference

No significant interference observed with available related molecules.

Regulatory Status

Research Use Only

Research Area

Biosimilars / Therapeutic Drug Monitoring / Antibody Drug Conjugates

ELISA Type

Direct Sandwich Assay

Storage Temperature

Store the unopened product at 2-8C. Do not use past expiration date.