KRIBIOLISA™ Vantictumab ELISA

SKU: KBI1717 Category:

58,000.00

Enzyme Immunoassay for the estimation of Vantictumab in serum and plasma.

About the kit:
– Uses anti-idiotypic monoclonal antibodies which ensures higher specificity, and low cross reactivity.
– Recovery rates are between 85 – 115%
– Validated as per US FDA guidelines for Bioassays
– Precision CV<10%


Availability: 3 – 4 Weeks | Pack Size: 1 x 96 wells



Description

Background:
Vantictumab Vantictumab, is a monoclonal antibody that targets a protein called Frizzled homolog 7 (FZD7). FZD7 is a receptor involved in the Wnt signaling pathway, which plays a role in various cellular processes including cell growth and development. By targeting FZD7, vantictumab aims to disrupt the Wnt signaling pathway in certain types of cancer cells.Vantictumab has been primarily studied in the context of solid tumors, including breast cancer, pancreatic cancer, and lung cancer. It has been investigated both as a standalone therapy and in combination with other anti-cancer agents. a human IgG2 monoclonal antibody designed for the treatment of cancer.

Intended Use:
For Estimation of Vantictumab in human serum and plasma. Please note the kit has not been optimized to be used for any other animal species. Should you require a specific sera tested, please connect with us at sales@krishgen.com for optimization.









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Additional information

Species

Human

Biomarker Estimation

measures free drug

Sample Type

Serum (100 ul), EDTA Plasma (100 ul), Heparin Plasma (100 ul), Citrate Plasma (100 ul)

Calibration Range

0 ng/ml – 2000 ng/ml

Detection Method

Colorimetric

Specificity

80% – 120% to Vantictumab

Cross Reactivity

< 0.5% cross-reactivity observed with related biomarker.

Interference

No significant interference observed with available related molecules.

Regulatory Status

Research Use Only

Research Area

Biosimilars / Therapeutic Drug Monitoring

Alternate Names / Synonyms

OMP-18R5, Vantictumab

Drug Bank Accession Number

DB12956

ELISA Type

Direct Sandwich Assay

Storage Temperature

Store the unopened product at 2-8 Deg C. Do not use past expiration date.

Validation

The kit uses a biosimilar research grade standard / calibrator. The standard / calibrator has been validated against WHO/NIBSC standard and/or against commercially sourced innovator drug where available. Please refer the IFU for more details.

Disclaimer

Trade name indicated is for reference purposes only. It does not reflect any licences or patent usage. The tradename is the registered trademark of the respective owners only.

Long Name

Protein Based Therapies – Monoclonal Antibody