KRIBIOLISA™ Vopratelimab ELISA

SKU: KBI1735 Category:

58,000.00

Enzyme Immunoassay for the estimation of Vopratelimab in serum and plasma.

About the kit:
– Uses anti-idiotypic monoclonal antibodies which ensures higher specificity, and low cross reactivity.
– Recovery rates are between 85 – 115%
– Validated as per US FDA guidelines for Bioassays
– Precision CV<10%


Availability: 3 – 4 Weeks | Pack Size: 1 x 96 wells



Description

Background:
Vopratelimab is an investigational monoclonal antibody that targets an immune checkpoint protein called TIM-3 (T-cell immunoglobulin and mucin-domain containing-3). TIM-3 is expressed on the surface of certain immune cells, including T cells, and plays a role in regulating immune responses. By binding to TIM-3, vopratelimab aims to modulate the immune system and potentially enhance anti-tumor immune responses. It is being studied as a potential immunotherapy for various types of cancer, including solid tumors and hematological malignancies.

Intended Use:
For Estimation of Vopratelimab in human serum and plasma. Please note the kit has not been optimized to be used for any other animal species. Should you require a specific sera tested, please connect with us at sales@krishgen.com for optimization.









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Additional information

Species

Human

Biomarker Estimation

measures free drug

Sample Type

Serum (100 ul), EDTA Plasma (100 ul), Heparin Plasma (100 ul), Citrate Plasma (100 ul)

Calibration Range

0 ng/ml – 2000 ng/ml

Detection Method

Colorimetric

Specificity

80% – 120% to Vopratelimab

Cross Reactivity

< 0.5% cross-reactivity observed with related biomarker.

Interference

No significant interference observed with available related molecules.

Regulatory Status

Research Use Only

Research Area

Biosimilars / Therapeutic Drug Monitoring

Entez Gene ID

JTX-2011 Human

Alternate Names / Synonyms

Vopratelimab

Drug Bank Accession Number

DB15378

ELISA Type

Direct Sandwich Assay

Storage Temperature

Store the unopened product at 2-8 Deg C. Do not use past expiration date.

Validation

The kit uses a biosimilar research grade standard / calibrator. The standard / calibrator has been validated against WHO/NIBSC standard and/or against commercially sourced innovator drug where available. Please refer the IFU for more details.

Disclaimer

Trade name indicated is for reference purposes only. It does not reflect any licences or patent usage. The tradename is the registered trademark of the respective owners only.

Long Name

Protein Based Therapies – Monoclonal Antibody