Description
Background:
Dapirolizumab pegol is an humanisied Fab fragment and polyethylene glycol conjugate, and acts as a CD40 Ligand antagonist.It has shown therapeutic potential in patients with Systemic Lupus Erythematosus, relapsing multiple sclerosis, relapsing-remitting multiple sclerosis (RRMS) and secondary progressive multiple sclerosis (SPMS). CD40L is a costimulatory molecule expressed on activated T cells which signals to professional antigen-presenting cells, but it is also expressed on platelets and monocytes, natural killer (NK) cells, mast cells, and basophils under inflammatory conditions.
Intended Use:
For Estimation of Dapirolizumab Pegol in human serum and plasma. Krishgen’s range of KRIBIOLISA kits are developed using the high quality raw materials and are thoroughly validated for accuracy and precison. They allow quantification of serum or plasma protein drug levels, and can be used for biosimilar and generics research to understand pharmacokinetic properties of the drug. Please note the kit has not been optimized to be used for any other animal species. Should you require a specific sera tested, please connect with us for optimisation.
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