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Interferon gamma (IFN-) is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical to both innate and adaptive immunity, and functions as the primary activator of macrophages, in addition to stimulating natural killer cells and neutrophils.
ELISA Features include:- Ready to use protocol- Standardisation and High Reproducibility- Lot to Lot Consistency- Accuracy and PrecisionValidated against seven points for a”GOLD RING”Standard Quality ELISA – the benchmark sign for Krishgen quality. The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be serum, plasma, biological fluids and cell culture supernatant.
Background:
Interferon-gamma (IFN-gamma) is a cytokine that plays a crucial role in the immune system’s response to infections, particularly in the context of cellular immunity. It is produced by activated T lymphocytes and natural killer (NK) cells in response to antigenic stimulation. IFN-gamma has diverse functions, including enhancing the activity of immune cells, promoting antigen presentation, and modulating the immune response. In clinical settings, IFN-gamma is used as a diagnostic tool, particularly in assessing cell-mediated immunity. The Quantiferon-TB Gold test, for example, utilizes IFN-gamma release assays to detect the presence of Mycobacterium tuberculosis infection by measuring the IFN-gamma released from T cells exposed to specific tuberculosis antigens. Additionally, IFN-gamma is explored in immunotherapy for various diseases, including certain cancers and autoimmune disorders, where it can exert antitumor or immunomodulatory effects. Its versatile applications in both diagnostics and therapeutics make IFN-gamma a key player in understanding and harnessing the immune system’s capabilities.
The GENLISA Human Interferon Gamma (IFNgamma / IFNg) ELISA includes features like:
– Ready to use protocol with break-apart wells for ease of use
– Standardisation and High Reproducibility
– Lot to Lot Consistency
– Accuracy and Precision
Validated against seven points for a “GOLD RING” Standard Quality ELISA – the benchmark sign for Krishgen Quality. The The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be human serum, plasma, biological fluids and cell culture supernatant. The kit uses indirect sandwich assay with double antibodies – capture and detection to ensure a high degree of sensitivity and specificity in the estimation of Interferon Gamma (IFNgamma / IFNg);
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