Description
Background:
Zonulin is a protein that modulates the permeability of tight junctions between cells in the epithelial lining of the intestines. Tight junctions play a crucial role in regulating the passage of molecules and ions through the intestinal barrier, maintaining gut integrity, and preventing the translocation of harmful substances from the gut lumen into systemic circulation. Dysregulation of Zonulin has been implicated in various gastrointestinal disorders, autoimmune diseases, and metabolic conditions. The Human Zonulin ELISA Kit offers a reliable method for quantifying Zonulin levels in human serum, plasma, and stool samples, facilitating studies aimed at understanding intestinal permeability and its implications for health and disease.
By quantifying Zonulin levels, researchers can assess gut permeability, mucosal integrity, and the integrity of the blood-brain barrier. Furthermore, aberrant Zonulin expression or activity is associated with conditions such as inflammatory bowel disease (IBD), celiac disease, irritable bowel syndrome (IBS), and metabolic syndrome. Understanding Zonulin pathways is crucial for developing targeted interventions aimed at restoring intestinal barrier function and mitigating the progression of gastrointestinal and systemic disorders.
Ongoing studies are investigating the molecular mechanisms underlying Zonulin regulation, its interactions with gut microbiota, and its involvement in immune responses and inflammatory pathways. Furthermore, researchers are exploring the therapeutic potential of Zonulin modulators for treating gastrointestinal disorders and associated systemic conditions. The Human Zonulin ELISA Kit is a valuable tool driving innovative research and paving the way for personalized interventions in gastroenterology and immunology.
Elevate your research endeavors with the Human Zonulin ELISA Kit and unravel the complexities of intestinal barrier function. Accelerate discoveries, advance knowledge, and contribute to groundbreaking advancements in gastroenterology and personalized medicine.
Validated against seven points for a “GOLD RING” Standard Quality ELISA – the benchmark sign for Krishgen Quality. The The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be human serum, plasma, biological fluids and cell culture supernatant. The kit uses indirect sandwich assay with double antibodies – capture and detection to ensure a high degree of sensitivity and specificity in the estimation of Zonulin;
If you have published a paper by using any of our ELISA since 01/01/2023, kindly fill out the “Krishgen Publication Reward Application Form” with complete information and send it by at email: kbiinfo@krishgen.com, with the subject “Krishgen Publication Reward”. We will get back to you with the Amazon / Krishgen Credit Reward after we confirm it ASAP!