KRIBIOLISA Neutralizing Antibodies to Vosoritide ELISA

SKU: KBN4176

Rs 195,000.00

Enzyme Immunoassay for the estimation of Neutralizing Antibodies to Vosoritide in human serum. Lead time 6 weeks.

 

Guaranteed Safe Checkout

All our kits are manufactured under ISO 13485.

KRIBIOLISA Neutralizing Antibody Vorsoritide ELISA includes features like:
– Ready to use protocol with break-apart wells for ease of use
– Standardisation and High Reproducibility
– Lot to Lot Consistency
– Accuracy and Precision,

Background: This ELISA qualitatively measures the neutralizing antibodies to the referenced therapeutic protein or biomolecule in biological samples, supporting pharmacokinetic, bioanalytical, and research applications. IT uses the classical methodology of utlizing the interaction between the therapeutic protein and its receptor to offer a competitive ligand binding assay.

Validated against seven points for a “GOLD RING” Standard Quality ELISA – the benchmark sign for Krishgen Quality. KRIBIOLISA ELISA kit is used for assessing the neutralizing antibody to the specific biomarker in samples analytes which may be human serum, plasma, biological fluids and cell culture supernatant. The kit uses indirect sandwich assay with double antibodies / recombinant proteins – capture and detection to ensure a high degree of sensitivity and specificity in the estimation of the analyte. Extensive validation has been done on these kits. Please ask for our validation guide if not available on our product page. Incase you wish us to customize the kit, connect with us at sales1@krishgen.com

Additional information

Pack Type

1 x 96 wells, break-apart wells

Assay Range

Qualitative

Sensitivity

Qualitative

Species Reactivity

Homo Sapiens (Human)

Short Name

Vosoritide Neutralizing Antibody ELISA

Interference

Preparations of the known factors were assayed for interference. No significant interference was observed.

Specificity

The assay uses anti idiotypic (humanized) antibody for capture and / or recombinant protein expressed in mamalian cells.

Principle Of Assay

Competitive ELISA

ELISA Interpretation

Qualitative Results Intepretation

Regulatory Status

Research Use Only. Kit is developed and validated as per ICH/EMA/FDA guidelines. Ask for our detailed validation guide at sales1@krishgen.com

Sample Dilution

Dilute at 1:1000 with the Sample Diluent provided in the kit. Please refer to the IFU enclosed with the kit supplied for specific guidance.

Detection Method

Absorbance measured at 450nm, Colorimetric

Standards Available

Controls – Positive, Negative

Sample Type

please connect with us to optimize the kit accordingly., Serum and Plasma. Note the kit has been validated using human matrices only. For any other matrix

Product Catalog

Monoclonal Antibodies

Therapeutic / Biology Type

Immunology / Biologics

Biological Pathway

Fibroblast Growth Factor Receptor 3 (FGFR3)

KEGG Target Pathway

hsa04066; hsa04062

Biomarker / Protein

Vosoritide

Conjugate-Enzyme Reaction

Uses stable HRP Enzyme Conjugate with (single component kinetic) and TMB Chromogenic Substrate for color development.

Shipping Temperature

Shipped at Room Temperature or in gel pack to maintain temperature at 2-8 degrees Celsius

Storage Temperature

if all the wells in the kit are not being used, store the unused wells in the foil pouch containing the desiccant pack, The kit (2-8 Degree Celsius) and its components are to be stored as indicated in the IFU (instructions for use). To ensure quality of your results

Shelf Life Available

8 -10 months at time of shipping

Reactome Pathway ID

R-HSA-2393917 (Growth hormone receptor signaling); R-HSA-162582 (Signal Transduction)

Research Area

Bone Growth Biology; Genetic Skeletal Disorders

Disclaimer

pathways, research areas are for informational purpose only.