Krishzyme Endo-beta-N-acetylglucosaminidase F3 (Endo F3) (lyophilized)

Krishzyme Endo-beta-N-acetylglucosaminidase F3 (Endo F3) cleaves in beta(1-4) link in between the two core GlcNAcs of asparagine linked glycans. It cleaves this link on core-fucosylated structures. Krishzyme Endo F3 can be applied to workflows alone or in conjunction with Krishzyme Swift PNGase-F to allow for structural characterization of core-fucosylated glycans in tissues while maintaining spatial localization. A major drawback of MALDI Imaging is the inability to differentiate core-fucosylated glycans from outer-arm fucosylated glycans. This issue is alleviated through by using Krishzyme Endo F3 due to its specificity for core-fucosylated structures. Krishzyme Endo F3 in a lyophilized format that is perfectly suitable for use in solution-based analyses.