Krishzyme high-purity Ides Protease is an efficient and reliable enzymatic tool for studying antibody-based drugs and Fc fusion proteins. Ides Protease (Immunoglobulin G Degrading Enzyme) is a protease derived from Streptococcus equi subspecies zooepidemicus, known for its exceptional substrate specificity. It cleaves IgG at a specific site in the hinge region, generating intact F(ab )2 fragments and Fc fragments. Krishzyme Ides Protease has a high specificity which cleaves IgG, compatible with human IgG1, IgG2, IgG3, IgG4, and monkey, sheep, rabbit, humanized, and chimeric IgGs. It is ideal for characterizing therapeutic antibodies, Fc fusion proteins, and antibody-drug conjugates, providing reliable experimental support. Krishzyme Ides Protease is produced via recombinant E. coli expression with >95% purity, free of impurities, and high stability. Applications: – Structural characterization of therapeutic antibodies. – Functional analysis of Fc fusion proteins. – Antibody-drug conjugate (ADC) studies. – Antibody-based drug development.
Additional information
| Pack Size | 1000 U |
|---|---|
| Shipping Temperature | – 20 Deg C, dry ice |
| Storage Temperature | Frost free freezer at -20 Deg Celsius |
| Regulatory Status | For Research Use Only |
