KRIBIOLISA™ Ramucirumab (CYRAMZA) ELISA

SKU: KBI1579 Category:

₹58,000.00

Enzyme Immunoassay for the estimation of Ramucirumab in serum and plasma.

About the kit:
– Uses anti-idiotypic monoclonal antibodies which ensures higher specificity, and low cross reactivity.
– Recovery rates are between 85 – 115%
– Validated as per US FDA guidelines for Bioassays
– Precision CV<10%

Availability: 3 – 4 Weeks | Pack Size: 1 x 96 wells

Description

Background:
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab is also an angiogenesis inhibitor.

Intended Use:
For Estimation of Ramucirumab (CYRAMZA) in human serum and plasma. Please note the kit has not been optimized to be used for any other animal species. Should you require a specific sera tested, please connect with us at sales@krishgen.com for optimization.

If you have published a paper by using any of our ELISA since 01/01/2023, kindly fill out the “Krishgen Publication Reward Application Form” with complete information and send it by at email: info@krishgen.com, with the subject “Krishgen Publication Reward”. We will get back to you with the Amazon / Krishgen Credit Reward after we confirm it ASAP!

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Additional information

Calibration Range

0 ng/ml – 2000 ng/ml
Detection Method

Colorimetric
Specificity

80% – 120% to Ramucirumab
Cross Reactivity

< 0.5% cross-reactivity observed with related biomarker.
Interference

No significant interference observed with available related molecules.
Regulatory Status

Research Use Only
Storage Temprature

Store the unopened product at 2-8 Degree Celcius. Concentrated detection conjugate should be stored at -20 Degree Celcius. Do not use past expiration date.
Shipping Temperature

2-8 Degree Celcius. Concentrated detection conjugate ship at -20 Degree Celcius in a second box. Freight applicable for both.
Research Area

Biosimilars / Therapeutic Drug Monitoring
Entez Gene ID

1121B Human
Alternate Names / Synonyms

Ramucirumab
Alternate Drug Brand Names

Cyramza
Drug Bank Accession Number

DB05578
ELISA Type

Direct Sandwich Assay
Validation

The kit uses a biosimilar research grade standard / calibrator. The standard / calibrator has been validated against WHO/NIBSC standard and/or against commercially sourced innovator drug where available. Please refer the IFU for more details.

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