KRIBIOLISA™ Runimotamab ELISA

SKU: KBI1766 Category:

85,000.00

Enzyme Immunoassay for the estimation of Runimotamab in serum and plasma.

About the kit:
– Uses two anti-idiotypic monoclonal antibodies in direct sandwich format which ensures higher specificity, and low cross reactivity.
– Recovery rates are between 85 – 115%
– Validated as per US FDA guidelines for Bioassays
– Precision CV<10%


Availability: 3 – 4 weeks | Pack Size: 1 x 96 wells



Description

Background:
Runimotamab a is HER2/anti-CD3 T-cell-dependent bispecific mAb considered to present both immunostimulatory and antineoplastic effects. By binding simultaneously to CD3-expressing T cells and HER2- expressing tumour cells it creates a bridge between these latter to potentiate the T-cell cytotoxic effect against HER2+ tumour cells. An ongoing phase I trial is currently assessing Runimotamab on locally advanced or metastatic HER2-expressing solid tumours.

Intended Use:
For Estimation of Runimotamab in human serum and plasma. Krishgen’s range of KRIBIOLISA kits are developed using the high quality raw materials and are thoroughly validated for accuracy and precison. They allow quantification of serum or plasma protein drug levels, and can be used for biosimilar and generics research to understand pharmacokinetic properties of the drug. Please note the kit has not been optimized to be used for any other animal species. Should you require a specific sera tested, please connect with us for optimisation.









If you have published a paper by using any of our ELISA since 01/01/2023, kindly fill out the “Krishgen Publication Reward Application Form” with complete information and send it by at email: info@krishgen.com, with the subject “Krishgen Publication Reward”. We will get back to you with the Amazon / Krishgen Credit Reward after we confirm it ASAP!

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Additional information

Sample Type

Serum (100 ul), EDTA Plasma (100 ul), Heparin Plasma (100 ul), Citrate Plasma (100 ul)

Calibration Range

0 ng/ml – 2000 ng/ml

Specificity

80% – 120% to Runimotamab

Cross Reactivity

< 0.5% cross-reactivity observed with related biomarker.

Interference

No significant interference observed with available related molecules.

Regulatory Status

Research Use Only

Research Area

Biosimilars / Therapeutic Drug Monitoring / Bispecific Antibodies

ELISA Type

Direct Sandwich Assay

Storage Temperature

Store the unopened product at 2-8C. Do not use past expiration date.