GTP, Guanosine-5′-triphosphate, which is a highly stable type of nucleotide. This compound and its sodium salt are the basic components of energy conversion in biological systems, and can be used in a variety of related applications in molecular biology, such as in vitro transcription (IVT), RNA amplification, siRNA synthesis, etc. In addition, GTP plays an important role in signal transduction as a phosphate or pyrophosphate messenger: GTP activates G proteins, which can induce multiple protein kinase-mediated cascades that cause a variety of cytological behavior, such as cell proliferation, differentiation, etc. In addition, GTP can also be used as a high-energy precursor of single nucleotides to participate in the enzymatic synthesis of DNA and RNA.
This product is a colorless and transparent aqueous solution prepared from ATP trisodium salt with a purity of ≥99% (HPLC), the concentration is 100 mM, pH (25°C) between 7.3-7.5. This preparation is free of DNase and RNase contamination and has been performance tested in transcription reaction.
